Sotagliflozin in diabetes with worsening heart failure
Bhatt DL, Szarek M, Steg PG
New England Journal of Medicine · 2022
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 10,584 participants. Evidence level: Ia.
循证研究：Sotagliflozin心肾结局研究
Key facts at a glance
- DOI
- 10.1056/NEJMoa2193159
- PMID
- 35303311
- Journal
- New England Journal of Medicine
- Year
- 2022
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 10584
- Intervention
- Sotagliflozin 200-400mg/天 vs 安慰剂
- Primary outcome
- 心血管死亡+心衰住院+急诊就诊
- Open access
- false
Study Overview
This randomized controlled trial enrolled 10,584 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 10,584 participants, investigating the effects of Sotagliflozin 200-400mg/天 vs 安慰剂 on 心血管死亡+心衰住院+急诊就诊.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy