DASH饮食模式对血压影响的临床试验

发布:2026年7月22日更新:2026年7月22日

Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM等

New England Journal of Medicine · 1997; 336(16):1117-1124

本综述评估Three carefully controlled diets for 8 weeks: a typical American control diet, a diet rich in fruits and vegetables, and the DASH combination diet (fruits, vegetables, low-fat dairy, and reduced saturated fat and cholesterol).与Change in systolic and diastolic blood pressure after 8 weeks的关系。纳入 459 例受试者。证据等级：Ib。

摘要速览

循证研究：DASH饮食治疗高血压

医学审核:WellAlly 编辑团队最后审核 2026年7月22日编辑政策

关键信息一览

DOI: 10.1056/nejm199704173361601
PMID: 9099655
期刊: New England Journal of Medicine
年份: 1997
卷: 336
期: 16
页码: 1117-1124
研究类型: RCT
证据等级: Ib
样本量: 459
干预措施: Three carefully controlled diets for 8 weeks: a typical American control diet, a diet rich in fruits and vegetables, and the DASH combination diet (fruits, vegetables, low-fat dairy, and reduced saturated fat and cholesterol).
主要终点: Change in systolic and diastolic blood pressure after 8 weeks
随访时长: 8 weeks
资金来源: NIH
效应量: DASH diet lowered systolic BP by 5.5 mm Hg and diastolic BP by 3.0 mm Hg more than control (p<0.001); larger effect (11.4/5.5 mm Hg) in those with hypertension
开放获取: 否

研究概述

本研究纳入 459 例受试者，探讨了Three carefully controlled diets for 8 weeks: a typical American control diet, a diet rich in fruits and vegetables, and the DASH combination diet (fruits, vegetables, low-fat dairy, and reduced saturated fat and cholesterol).对Change in systolic and diastolic blood pressure after 8 weeks的影响。

关键发现

研究结果为Change in systolic and diastolic blood pressure after 8 weeks提供了重要证据。

临床结论

详见原始文献。证据等级：Ib。

Abstract

"本随机对照试验共纳入 459 例受试者，探讨了Three carefully controlled diets for 8 weeks: a typical American control diet, a diet rich in fruits and vegetables, and the DASH combination diet (fruits, vegetables, low-fat dairy, and reduced saturated fat and cholesterol).对Change in systolic and diastolic blood pressure after 8 weeks的影响。

Funding & conflicts of interest

资金来源: NIH

COI: None reported

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