Aflibercept for wet age-related macular degeneration
Heier JS, Brown DM, Kaiser PK
New England Journal of Medicine · 2012
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 2,457 participants. Evidence level: Ia.
循证研究：Aflibercept治疗湿性黄斑变性
Key facts at a glance
- DOI
- 10.1056/NEJMoa1207649
- PMID
- 23023052
- Journal
- New England Journal of Medicine
- Year
- 2012
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 2457
- Intervention
- Aflibercept vs Ranibizumab
- Primary outcome
- 视力变化
- Open access
- false
Study Overview
This randomized controlled trial enrolled 2,457 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 2,457 participants, investigating the effects of Aflibercept vs Ranibizumab on 视力变化.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy