Eplerenone in patients with systolic heart failure
Zannad F, McMurray JJ, Krum H
New England Journal of Medicine · 2010
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 3,444 participants. Evidence level: Ia.
循证研究：醛固酮拮抗剂治疗心衰
Key facts at a glance
- DOI
- 10.1056/NEJMoa1009492
- PMID
- 20660825
- Journal
- New England Journal of Medicine
- Year
- 2010
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 3444
- Intervention
- Eplerenone 25-50mg/天 vs 安慰剂
- Primary outcome
- 心血管死亡或心衰住院
- Open access
- false
Study Overview
This randomized controlled trial enrolled 3,444 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 3,444 participants, investigating the effects of Eplerenone 25-50mg/天 vs 安慰剂 on 心血管死亡或心衰住院.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy