Dabigatran versus warfarin in atrial fibrillation
Connolly SJ, Ezekowitz MD, Yusuf S
New England Journal of Medicine · 2009
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 18,201 participants. Evidence level: Ia.
循证研究：房颤抗凝治疗：达比加群 vs 华法林
Key facts at a glance
- DOI
- 10.1056/NEJMoa0900471
- PMID
- 19689466
- Journal
- New England Journal of Medicine
- Year
- 2009
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 18201
- Intervention
- Dabigatran 110mg/150mg BID vs 华法林 INR 2-3
- Primary outcome
- 卒中或全身性栓塞
- Open access
- false
Study Overview
This randomized controlled trial enrolled 18,201 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 18,201 participants, investigating the effects of Dabigatran 110mg/150mg BID vs 华法林 INR 2-3 on 卒中或全身性栓塞.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy