Canagliflozin and Cardiovascular and Renal Events in Type 2 Diabetes
Neal B, Perkovic V, Mahaffey KW
New England Journal of Medicine · 2017
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 10,142 participants. Evidence level: Ia.
循证研究：卡格列净心血管评估研究
Key facts at a glance
- DOI
- 10.1056/NEJMoa1707100
- PMID
- 28304224
- Journal
- New England Journal of Medicine
- Year
- 2017
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 10142
- Intervention
- Canagliflozin 100mg/300mg vs 安慰剂
- Primary outcome
- 3P-MACE
- Open access
- false
Study Overview
This randomized controlled trial enrolled 10,142 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 10,142 participants, investigating the effects of Canagliflozin 100mg/300mg vs 安慰剂 on 3P-MACE.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy