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Dapagliflozin in patients with heart failure and reduced ejection fraction

Published: October 18, 2026Updated: October 18, 2026

McMurray JJ, Solomon SD, Inzucchi SE

New England Journal of Medicine · 2019

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 4,744 participants. Evidence level: Ia.

Quick summary

循证研究:达格列净治疗心衰研究

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1056/NEJMoa1914103
PMID
31492782
Journal
New England Journal of Medicine
Year
2019
Study type
rct
Evidence level
Ia
Sample size
4744
Intervention
Dapagliflozin 10mg/天 vs 安慰剂
Primary outcome
心血管死亡或心衰恶化 (复合)
Open access
false

Study Overview

This randomized controlled trial enrolled 4,744 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ia.

Abstract

"This randomized controlled trial enrolled 4,744 participants, investigating the effects of Dapagliflozin 10mg/天 vs 安慰剂 on 心血管死亡或心衰恶化 (复合).

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

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