A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group.
Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FMet al.
New England Journal of Medicine · 1997; 336(16):1117-1124
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 459 participants. Evidence level: Ib.
循证研究：DASH饮食治疗高血压
Key facts at a glance
- DOI
- 10.1056/nejm199704173361601
- PMID
- 9099655
- Journal
- New England Journal of Medicine
- Year
- 1997
- Volume
- 336
- Issue
- 16
- Pages
- 1117-1124
- Study type
- rct
- Evidence level
- Ib
- Sample size
- 459
- Intervention
- Three carefully controlled diets for 8 weeks: a typical American control diet, a diet rich in fruits and vegetables, and the DASH combination diet (fruits, vegetables, low-fat dairy, and reduced saturated fat and cholesterol).
- Primary outcome
- Change in systolic and diastolic blood pressure after 8 weeks
- Follow-up
- 8 weeks
- Funding
- NIH
- Effect size
- DASH diet lowered systolic BP by 5.5 mm Hg and diastolic BP by 3.0 mm Hg more than control (p<0.001); larger effect (11.4/5.5 mm Hg) in those with hypertension
- Open access
- false
Study Overview
This randomized controlled trial enrolled 459 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ib.
Abstract
"This randomized controlled trial enrolled 459 participants, investigating the effects of Three carefully controlled diets for 8 weeks: a typical American control diet, a diet rich in fruits and vegetables, and the DASH combination diet (fruits, vegetables, low-fat dairy, and reduced saturated fat and cholesterol). on Change in systolic and diastolic blood pressure after 8 weeks.
Funding & conflicts of interest
Funding: NIH
COI: None reported
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Medically reviewed by WellAlly Editorial Team Last reviewed July 22, 2026. · Read our editorial policy