Early goal-directed therapy for severe sepsis and septic shock
Rivers E, Nguyen B, Havstad S
New England Journal of Medicine · 2001
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 263 participants. Evidence level: Ib.
Evidence-Based Research: Early Goal Directed Therapy Sepsis
Key facts at a glance
- DOI
- 10.1056/NEJM200106073442206
- PMID
- 11445681
- Journal
- New England Journal of Medicine
- Year
- 2001
- Study type
- rct
- Evidence level
- Ib
- Sample size
- 263
- Intervention
- 早期目标导向治疗 vs 标准治疗
- Primary outcome
- 60天死亡率
- Open access
- false
Study Overview
This randomized controlled trial enrolled 263 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ib.
Abstract
"This randomized controlled trial enrolled 263 participants, investigating the effects of 早期目标导向治疗 vs 标准治疗 on 60天死亡率.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy