Finerenone and cardiovascular outcomes in CKD and type 2 diabetes
Bakris GL, Agarwal R, Anker SD
New England Journal of Medicine · 2021
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 7,437 participants. Evidence level: Ia.
循证研究：Finerenone糖尿病合并CKD研究
Key facts at a glance
- DOI
- 10.1056/NEJMoa2025845
- PMID
- 34449280
- Journal
- New England Journal of Medicine
- Year
- 2021
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 7437
- Intervention
- Finerenone 10-20mg/天 vs 安慰剂
- Primary outcome
- 心血管死亡+非致死性MI+卒中+心衰住院
- Open access
- false
Study Overview
This randomized controlled trial enrolled 7,437 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 7,437 participants, investigating the effects of Finerenone 10-20mg/天 vs 安慰剂 on 心血管死亡+非致死性MI+卒中+心衰住院.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy