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Adjunctive glucocorticoids in septic shock

Published: October 18, 2026Updated: October 18, 2026

Venkatesh B, Finfer S, Cohen J

JAMA · 2018

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 3,800 participants. Evidence level: Ib.

Quick summary

Evidence-Based Research: Glucocorticoid Septic Shock

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1001/jama.2018.11417
PMID
30476879
Journal
JAMA
Year
2018
Study type
rct
Evidence level
Ib
Sample size
3800
Intervention
氢化可的松+氟氢可的松 vs 安慰剂
Primary outcome
90天死亡率
Open access
false

Study Overview

This randomized controlled trial enrolled 3,800 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ib.

Abstract

"This randomized controlled trial enrolled 3,800 participants, investigating the effects of 氢化可的松+氟氢可的松 vs 安慰剂 on 90天死亡率.

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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

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