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Cardiovascular effects of intensive lifestyle intervention in type 2 diabetes

Published: October 18, 2026Updated: October 18, 2026

Look AHEAD Research Group, Pi-Sunyer X, Bray GA

New England Journal of Medicine · 2013

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 5,145 participants. Evidence level: Ib.

Quick summary

循证研究:强化生活方式干预糖尿病研究

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1056/NEJMoa1204792
PMID
22829934
Journal
New England Journal of Medicine
Year
2013
Study type
rct
Evidence level
Ib
Sample size
5145
Intervention
强化生活方式干预 vs 支持治疗
Primary outcome
心血管死亡、MI、卒中、心血管住院
Open access
false

Study Overview

This randomized controlled trial enrolled 5,145 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ib.

Abstract

"This randomized controlled trial enrolled 5,145 participants, investigating the effects of 强化生活方式干预 vs 支持治疗 on 心血管死亡、MI、卒中、心血管住院.

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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

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