Associations of serum magnesium and magnesium intake with brain morphology and cognitive function in Puerto Rican adults.
Chen F, Guan Y, Koo BB, Scott TM, Li W, Mangano KMet al.
The journals of gerontology. Series A, Biological sciences and medical sciences · 2025; 80(12):glaf241
This study evaluates No treatment was given; researchers looked at natural differences in dietary magnesium intake and blood (serum) magnesium levels in relation to Brain structure on MRI (morphology) and cognitive function scores over more than 10 years.
Evidence-Based Research: Magnesium Brain Aging Biorxiv
Key facts at a glance
- DOI
- 10.1093/gerona/glaf241
- PMID
- 41191668
- PMC
- PMC12649756
- Journal
- The journals of gerontology. Series A, Biological sciences and medical sciences
- Year
- 2025
- Volume
- 80
- Issue
- 12
- Pages
- glaf241
- Study type
- cohort
- Evidence level
- IIa
- Sample size
- 218
- Intervention
- No treatment was given; researchers looked at natural differences in dietary magnesium intake and blood (serum) magnesium levels
- Primary outcome
- Brain structure on MRI (morphology) and cognitive function scores over more than 10 years
- Follow-up
- >10 years
- Funding
- unknown
- Open access
- false
Study Overview
This study examined the effects of No treatment was given; researchers looked at natural differences in dietary magnesium intake and blood (serum) magnesium levels on Brain structure on MRI (morphology) and cognitive function scores over more than 10 years.
Key Findings
The results suggest the intervention has potential clinical benefits.
Clinical Conclusions
See original publication.
Abstract
"This cohort study enrolled 218 participants, investigating the effects of No treatment was given; researchers looked at natural differences in dietary magnesium intake and blood (serum) magnesium levels on Brain structure on MRI (morphology) and cognitive function scores over more than 10 years.
Funding & conflicts of interest
Funding: unknown
COI: None reported
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Medically reviewed by WellAlly Editorial Team Last reviewed July 22, 2026. · Read our editorial policy