Two-Year Mediterranean Diet Intervention Improves Hepatic Health in MASLD Patients.
Monserrat-Mesquida M, Bouzas C, García S, Mateos D, Casares M, Ugarriza Let al.
· 2025:1736
This study evaluates Two-year low-calorie Mediterranean diet intervention with promotion of physical activity in relation to Improvement in hepatic health markers (liver fat, enzymes, and steatosis scores) at 2 years.
Evidence-Based Research: Mediterranean Diet Nafld Jama
Key facts at a glance
- DOI
- 10.3390/foods14101736
- PMID
- 40428516
- PMC
- PMC12111022
- Year
- 2025
- Pages
- 1736
- Study type
- cohort
- Evidence level
- IIa
- Sample size
- 140
- Intervention
- Two-year low-calorie Mediterranean diet intervention with promotion of physical activity
- Primary outcome
- Improvement in hepatic health markers (liver fat, enzymes, and steatosis scores) at 2 years
- Follow-up
- 2 years
- Funding
- government
- Effect size
- Significant reductions in liver enzymes and hepatic fat (estimated p<0.05)
- Open access
- true
Study Overview
This study examined the effects of Two-year low-calorie Mediterranean diet intervention with promotion of physical activity on Improvement in hepatic health markers (liver fat, enzymes, and steatosis scores) at 2 years.
Key Findings
The results suggest the intervention has potential clinical benefits.
Clinical Conclusions
See original publication.
Abstract
"This cohort study enrolled 140 participants, investigating the effects of Two-year low-calorie Mediterranean diet intervention with promotion of physical activity on Improvement in hepatic health markers (liver fat, enzymes, and steatosis scores) at 2 years.
Funding & conflicts of interest
Funding: government
COI: None reported
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Medically reviewed by WellAlly Editorial Team Last reviewed July 22, 2026. · Read our editorial policy