Primary prevention of cardiovascular disease with Mediterranean diet
Estruch R, Ros E, Salas-Salvadó J
New England Journal of Medicine · 2013
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 7,447 participants. Evidence level: Ia.
循证研究：地中海饮食心血管预防
Key facts at a glance
- DOI
- 10.1056/NEJM1204792
- PMID
- 23697489
- Journal
- New England Journal of Medicine
- Year
- 2013
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 7447
- Intervention
- 地中海饮食（橄榄油/坚果）vs 低脂对照饮食
- Primary outcome
- 主要心血管事件（心梗/卒中/心血管死亡）
- Open access
- false
Study Overview
This randomized controlled trial enrolled 7,447 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 7,447 participants, investigating the effects of 地中海饮食（橄榄油/坚果）vs 低脂对照饮食 on 主要心血管事件（心梗/卒中/心血管死亡）.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy