Metformin and cardiovascular outcomes in type 2 diabetes
UK Prospective Diabetes Study Group
The Lancet · 1998
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 3,867 participants. Evidence level: Ia.
循证研究：二甲双胍心血管结局研究
Key facts at a glance
- DOI
- 10.1016/S0140-6736(98)07019-6
- PMID
- 9737553
- Journal
- The Lancet
- Year
- 1998
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 3867
- Intervention
- 二甲双胍 vs 传统治疗
- Primary outcome
- 糖尿病相关终点
- Open access
- false
Study Overview
This randomized controlled trial enrolled 3,867 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 3,867 participants, investigating the effects of 二甲双胍 vs 传统治疗 on 糖尿病相关终点.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy