Skip to content

N-acetylcysteine for idiopathic pulmonary fibrosis

Published: October 18, 2026Updated: October 18, 2026

Theidi N, Albera C, Bradford WZ

New England Journal of Medicine · 2014

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 535 participants. Evidence level: Ib.

Quick summary

Evidence-Based Research: Nac Idiopathic Pulmonary Fibrosis

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1056/NEJMoa1213688
PMID
23281978
Journal
New England Journal of Medicine
Year
2014
Study type
rct
Evidence level
Ib
Sample size
535
Intervention
N-乙酰半胱氨酸 vs 安慰剂
Primary outcome
FVC 变化
Open access
false

Study Overview

This randomized controlled trial enrolled 535 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ib.

Abstract

"This randomized controlled trial enrolled 535 participants, investigating the effects of N-乙酰半胱氨酸 vs 安慰剂 on FVC 变化.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

More rct studies

View all