Oral nirmatrelvir for COVID-19
Hammond J, Leister-Tebbe H, Gardner A
New England Journal of Medicine · 2022
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 2,246 participants. Evidence level: Ia.
循证研究：Paxlovid治疗COVID-19
Key facts at a glance
- DOI
- 10.1056/NEJMoa1208543
- PMID
- 35363957
- Journal
- New England Journal of Medicine
- Year
- 2022
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 2246
- Intervention
- Paxlovid (nirmatrelvir/ritonavir) vs 安慰剂
- Primary outcome
- COVID-19 相关住院或全因死亡
- Open access
- false
Study Overview
This randomized controlled trial enrolled 2,246 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 2,246 participants, investigating the effects of Paxlovid (nirmatrelvir/ritonavir) vs 安慰剂 on COVID-19 相关住院或全因死亡.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy