Preexposure prophylaxis for HIV prevention
Grant RM, Lama JR, Anderson PL
New England Journal of Medicine · 2010
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 2,499 participants. Evidence level: Ia.
循证研究：PrEP预防HIV
Key facts at a glance
- DOI
- 10.1056/NEJMx120001
- PMID
- 21672751
- Journal
- New England Journal of Medicine
- Year
- 2010
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 2499
- Intervention
- TDF/FTC (PrEP) vs 安慰剂
- Primary outcome
- HIV感染率
- Open access
- false
Study Overview
This randomized controlled trial enrolled 2,499 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 2,499 participants, investigating the effects of TDF/FTC (PrEP) vs 安慰剂 on HIV感染率.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy