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Trial of pregabalin for chronic low back pain

Published: October 18, 2026Updated: October 18, 2026

Mathieson S, Maher CG, Terblanche R

JAMA · 2016

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 229 participants. Evidence level: Ib.

Quick summary

循证研究:普瑞巴林治疗慢性腰背痛

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1001/jama.2016.27814
PMID
27434443
Journal
JAMA
Year
2016
Study type
rct
Evidence level
Ib
Sample size
229
Intervention
普瑞巴林 150-600mg/天 vs 安慰剂
Primary outcome
疼痛强度 (NRS)
Open access
false

Study Overview

This randomized controlled trial enrolled 229 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ib.

Abstract

"This randomized controlled trial enrolled 229 participants, investigating the effects of 普瑞巴林 150-600mg/天 vs 安慰剂 on 疼痛强度 (NRS).

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

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