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Semaglutide for NASH

Published: October 18, 2026Updated: October 18, 2026

Newsom PN, Burgart AM, Yang H

NEJM · 2021

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 320 participants. Evidence level: Ib.

Quick summary

循证研究:Semaglutide治疗NASH

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1056/NEJMsr2006817
PMID
32150467
Journal
NEJM
Year
2021
Study type
rct
Evidence level
Ib
Sample size
320
Intervention
Semaglutide 0.4mg/天 vs 安慰剂
Primary outcome
NASH逆转
Open access
false

Study Overview

This randomized controlled trial enrolled 320 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ib.

Abstract

"This randomized controlled trial enrolled 320 participants, investigating the effects of Semaglutide 0.4mg/天 vs 安慰剂 on NASH逆转.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

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