Canagliflozin and renal outcomes in type 2 diabetes
Parving HH, Andersson LB, Brenner BM
New England Journal of Medicine · 2016
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 1,648 participants. Evidence level: Ia.
循证研究：SGLT2i肾脏结局研究
Key facts at a glance
- DOI
- 10.1056/NEJMoa1604231
- PMID
- 27697934
- Journal
- New England Journal of Medicine
- Year
- 2016
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 1648
- Intervention
- 坎格列净 100mg/天 vs 安慰剂
- Primary outcome
- 肾小球滤过率下降、ESRD、死亡
- Open access
- false
Study Overview
This randomized controlled trial enrolled 1,648 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 1,648 participants, investigating the effects of 坎格列净 100mg/天 vs 安慰剂 on 肾小球滤过率下降、ESRD、死亡.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy