Skip to content

Citalopram for treatment of major depression

Published: October 18, 2026Updated: October 18, 2026

Nemeroff CB, Heimsoth DJ, Kristol J

JAMA · 2006

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 405 participants. Evidence level: Ib.

Quick summary

循证研究:西酞普兰治疗抑郁症

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1001/jama.2006.55
PMID
16439662
Journal
JAMA
Year
2006
Study type
rct
Evidence level
Ib
Sample size
405
Intervention
Citalopram vs 安慰剂
Primary outcome
抑郁症状改善 (HAMD-17)
Open access
false

Study Overview

This randomized controlled trial enrolled 405 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ib.

Abstract

"This randomized controlled trial enrolled 405 participants, investigating the effects of Citalopram vs 安慰剂 on 抑郁症状改善 (HAMD-17).

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

More rct studies

View all