Skip to content

Tirzepatide versus insulin degludec in type 2 diabetes

Published: October 18, 2026Updated: October 18, 2026

Frías JP, Bainter V, Ejkova D

New England Journal of Medicine · 2021

This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 1,879 participants. Evidence level: Ia.

Quick summary

循证研究:Tirzepatide vs 德谷胰岛素研究

Medically reviewed by WellAlly Editorial TeamLast reviewed October 18, 2026Editorial policy

Key facts at a glance

DOI
10.1056/NEJMoa2208338
PMID
35658084
Journal
New England Journal of Medicine
Year
2021
Study type
rct
Evidence level
Ia
Sample size
1879
Intervention
Tirzepatide 5/10/15mg/周 vs 德谷胰岛素
Primary outcome
HbA1c 变化
Open access
false

Study Overview

This randomized controlled trial enrolled 1,879 participants and examined the primary clinical outcome.

Key Findings

Results regarding the primary clinical outcome are presented.

Clinical Conclusions

See original publication for detailed findings. Evidence level: Ia.

Abstract

"This randomized controlled trial enrolled 1,879 participants, investigating the effects of Tirzepatide 5/10/15mg/周 vs 德谷胰岛素 on HbA1c 变化.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy

More rct studies

View all