Tranexamic acid in trauma hemorrhage
CRASH-2 trial collaborators, Roberts I, Shakur H
The Lancet · 2011
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 20,211 participants. Evidence level: Ia.
循证研究：氨甲环酸治疗创伤出血
Key facts at a glance
- DOI
- 10.1016/S0140-6736(11)60278-X
- PMID
- 21719437
- Journal
- The Lancet
- Year
- 2011
- Study type
- rct
- Evidence level
- Ia
- Sample size
- 20211
- Intervention
- 氨甲环酸 1g 10min内 + 1g 8h vs 安慰剂
- Primary outcome
- 全因死亡
- Open access
- false
Study Overview
This randomized controlled trial enrolled 20,211 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ia.
Abstract
"This randomized controlled trial enrolled 20,211 participants, investigating the effects of 氨甲环酸 1g 10min内 + 1g 8h vs 安慰剂 on 全因死亡.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy