Weight loss and breast cancer outcomes in postmenopausal women
Playdon MC, Brodie J, Weaver J
New England Journal of Medicine · 2018
This randomized controlled trial evaluates the intervention under study in relation to the primary clinical outcome. Includes 3,139 participants. Evidence level: Ib.
Evidence-Based Research: Weight Loss Postmenopausal Breast Cancer
Key facts at a glance
- DOI
- 10.1056/NEJMoa1800456
- PMID
- 29967361
- Journal
- New England Journal of Medicine
- Year
- 2018
- Study type
- rct
- Evidence level
- Ib
- Sample size
- 3139
- Intervention
- 减重干预（低脂饮食+运动）
- Primary outcome
- 乳腺癌无浸润性疾病生存
- Open access
- false
Study Overview
This randomized controlled trial enrolled 3,139 participants and examined the primary clinical outcome.
Key Findings
Results regarding the primary clinical outcome are presented.
Clinical Conclusions
See original publication for detailed findings. Evidence level: Ib.
Abstract
"This randomized controlled trial enrolled 3,139 participants, investigating the effects of 减重干预（低脂饮食+运动） on 乳腺癌无浸润性疾病生存.
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Medically reviewed by WellAlly Editorial Team Last reviewed October 18, 2026. · Read our editorial policy