Physical activity and survival after breast cancer diagnosis.
Holmes MD, Chen WY, Feskanich D, Kroenke CH, Colditz GA.
JAMA · 2005; 293(20):2479-2486
This study evaluates Self-reported physical activity levels after diagnosis (measured in MET-hours per week, such as walking or other exercise; observational comparison of activity categories, not a prescribed program) in relation to Risk of death from breast cancer.
Evidence-Based Research: Exercise Cancer Survival Jnci
Key facts at a glance
- DOI
- 10.1001/jama.293.20.2479
- PMID
- 15914748
- Journal
- JAMA
- Year
- 2005
- Volume
- 293
- Issue
- 20
- Pages
- 2479-2486
- Study type
- cohort
- Evidence level
- IIa
- Sample size
- 2987
- Intervention
- Self-reported physical activity levels after diagnosis (measured in MET-hours per week, such as walking or other exercise; observational comparison of activity categories, not a prescribed program)
- Primary outcome
- Risk of death from breast cancer
- Follow-up
- Median 8 years
- Funding
- NIH
- Effect size
- RR 0.50 (95% CI 0.31-0.82) for 9-14.9 MET-h/week vs <3 MET-h/week, p for trend=0.004
- Open access
- false
Study Overview
This study examined the effects of Self-reported physical activity levels after diagnosis (measured in MET-hours per week, such as walking or other exercise; observational comparison of activity categories, not a prescribed program) on Risk of death from breast cancer.
Key Findings
The results suggest the intervention has potential clinical benefits.
Clinical Conclusions
See original publication.
Abstract
"This cohort study enrolled 2,987 participants, investigating the effects of Self-reported physical activity levels after diagnosis (measured in MET-hours per week, such as walking or other exercise; observational comparison of activity categories, not a prescribed program) on Risk of death from breast cancer.
Funding & conflicts of interest
Funding: NIH
COI: None reported
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Medically reviewed by WellAlly Editorial Team Last reviewed July 22, 2026. · Read our editorial policy