益生元和益生菌治疗抑郁和焦虑
Liu RT, Walsh RFL, Sheehan AE.
Neuroscience & Biobehavioral Reviews · 2019:13-23
本综述评估Prebiotic supplements (fiber compounds that feed gut bacteria) or probiotic supplements (live beneficial bacteria strains) in various doses and combinations, compared with placebo or control与Change in depression and anxiety symptom scores on standard questionnaires的关系。纳入 1,931 例受试者。证据等级：Ia。
循证研究：益生菌与抑郁和焦虑
关键信息一览
- DOI
- 10.1016/j.neubiorev.2019.03.023
- PMID
- 31004628
- PMC
- PMC6584030
- 期刊
- Neuroscience & Biobehavioral Reviews
- 年份
- 2019
- 页码
- 13-23
- 研究类型
- 荟萃分析
- 证据等级
- Ia
- 样本量
- 1931
- 干预措施
- Prebiotic supplements (fiber compounds that feed gut bacteria) or probiotic supplements (live beneficial bacteria strains) in various doses and combinations, compared with placebo or control
- 主要终点
- Change in depression and anxiety symptom scores on standard questionnaires
- 随访时长
- Typically 4–8 weeks (varied by trial)
- 资金来源
- 未知
- 效应量
- Probiotics for depression: SMD -0.24 (95% CI -0.36 to -0.12); probiotics for anxiety: SMD -0.12 (95% CI -0.24 to -0.01); prebiotics: no significant effect
- 开放获取
- 否
研究概述
本研究纳入 1,931 例受试者，探讨了Prebiotic supplements (fiber compounds that feed gut bacteria) or probiotic supplements (live beneficial bacteria strains) in various doses and combinations, compared with placebo or control对Change in depression and anxiety symptom scores on standard questionnaires的影响。
关键发现
研究结果为Change in depression and anxiety symptom scores on standard questionnaires提供了重要证据。
临床结论
详见原始文献。证据等级：Ia。
Abstract
"本系统综述共纳入 1,931 例受试者，探讨了Prebiotic supplements (fiber compounds that feed gut bacteria) or probiotic supplements (live beneficial bacteria strains) in various doses and combinations, compared with placebo or control对Change in depression and anxiety symptom scores on standard questionnaires的影响。
Funding & conflicts of interest
资金来源: unknown
COI: None reported
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