维生素D补充预防急性呼吸道感染
Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P等
BMJ · 2017:i6583
本综述评估Vitamin D supplements given by mouth in various doses (daily, weekly, or monthly) compared with placebo or no vitamin D与Occurrence of any acute respiratory tract infection (such as colds, flu, or bronchitis)的关系。纳入 11,321 例受试者。证据等级：Ia。
循证研究：维生素D补充与急性呼吸道感染
关键信息一览
- DOI
- 10.1136/bmj.i6583
- PMID
- 28202713
- PMC
- PMC5310969
- 期刊
- BMJ
- 年份
- 2017
- 页码
- i6583
- 研究类型
- 荟萃分析
- 证据等级
- Ia
- 样本量
- 11321
- 干预措施
- Vitamin D supplements given by mouth in various doses (daily, weekly, or monthly) compared with placebo or no vitamin D
- 主要终点
- Occurrence of any acute respiratory tract infection (such as colds, flu, or bronchitis)
- 随访时长
- Varied by trial (median around 6 months, range 1 month to several years)
- 资金来源
- government
- 效应量
- Adjusted odds ratio 0.88 (95% CI 0.81-0.96) overall; stronger benefit (OR 0.30) in those with severe deficiency
- 注册号
- CRD42014013953
- 开放获取
- 是
研究概述
本研究纳入 11,321 例受试者，探讨了Vitamin D supplements given by mouth in various doses (daily, weekly, or monthly) compared with placebo or no vitamin D对Occurrence of any acute respiratory tract infection (such as colds, flu, or bronchitis)的影响。
关键发现
研究结果为Occurrence of any acute respiratory tract infection (such as colds, flu, or bronchitis)提供了重要证据。
临床结论
详见原始文献。证据等级：Ia。
Abstract
"本系统综述共纳入 11,321 例受试者，探讨了Vitamin D supplements given by mouth in various doses (daily, weekly, or monthly) compared with placebo or no vitamin D对Occurrence of any acute respiratory tract infection (such as colds, flu, or bronchitis)的影响。
Funding & conflicts of interest
资金来源: government
COI: Some authors reported research grants or advisory roles linked to vitamin D; full disclosures provided in the paper
本信息仅供教育用途，不能替代专业医疗建议、诊断或治疗。
本内容仅供一般信息和教育用途，不能替代专业医疗建议、诊断或治疗。对于任何医疗问题，请务必咨询合格的医疗服务提供者；切勿因阅读本站内容而忽视专业医疗建议或推迟就医。
如果您认为自己可能出现医疗紧急情况，请立即拨打当地急救电话或前往最近的急诊科。
医学审核:WellAlly 编辑团队 最后审核 2026年7月22日. · 阅读我们的编辑政策